Read the Medication Guide provided by your pharmacist before you start using sublingual buprenorphine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

a b c "Buprenorphine". SAMHSA Center for Substance Abuse Treatment (CSAT). July 2019. Archived from the original on 20 August 2020 . Retrieved 9 January 2020.Ling W, Hillhouse MP, Saxon AJ, Mooney LJ, Thomas CM, Ang A, etal. (August 2016). "Buprenorphine + naloxone plus naltrexone for the treatment of cocaine dependence: the Cocaine Use Reduction with Buprenorphine (CURB) study". Addiction. 111 (8): 1416–1427. doi: 10.1111/add.13375. PMC 4940267. PMID 26948856. {{ cite journal}}: CS1 maint: overridden setting ( link) You or the person who's unwell may also have a rash that's swollen, raised, itchy, blistered or peeling.

Ruiz P, Strain EC (2011). Lowinson and Ruiz's Substance Abuse: A Comprehensive Textbook. Lippincott Williams & Wilkins. p.439. ISBN 978-1-60547-277-5. Archived from the original on 14 January 2023 . Retrieved 14 March 2016. ARCHIVED - Report Stakeholder Workshop on a National Buprenorphine Program". Health Canada. 6 December 2004. Archived from the original on 26 March 2020 . Retrieved 10 January 2020. Side effects may include respiratory depression (decreased breathing), sleepiness, adrenal insufficiency, QT prolongation, low blood pressure, allergic reactions, constipation, and opioid addiction. [14] [18] Among those with a history of seizures, a risk exists of further seizures. [14] Opioid withdrawal following stopping buprenorphine is generally less severe than with other opioids. [14] Whether use during pregnancy is safe is unclear, but use while breastfeeding is probably safe, since the dose the infant receives is 1-2% that of the maternal dose, on a weight basis. [19] [14] With the inclusion of another opioid, Suboxone was considered slightly less addictive, though the differences are still heavily debated.Common (1% to 10%): Vomiting, dyspepsia, dry mouth, stomach discomfort, upper abdominal pain, flatulence patches release 5 micrograms, 10 micrograms, 15 micrograms or 20 micrograms every hour for 7 days, or 35 micrograms, 52.5 micrograms or 70 micrograms every hour for 3 or 4 days In positron emission tomography (PET) imaging studies, buprenorphine was found to decrease whole-brain MOR availability due to receptor occupancy by 41% (i.e., 59% availability) at 2mg, 80% (i.e., 20% availability) at 16mg, and 84% (i.e., 16% availability) at 32mg. [76] [77] [78] [79] Other actions [ edit ] It's best not to drink alcohol when you first start buprenorphine treatment. You're more likely to get side effects such as feeling sleepy or drowsy.