My favorite piece is the red one, because the large rods really dig into my soles. With enough time, I walk away feeling refreshed not only in my feet but also in my lower legs. That’s a plus, especially given that I have #plantarfasciitis. Ikeda R, Cha M, Ling J, Jia Z, Coyle D, Gu JG (2014) Merkel cells transduce and encode tactile stimuli to drive Abeta-afferent impulses. Cell 157:664–675 Carvell GE, Simons DJ (1990) Biometric analyses of vibrissal tactile discrimination in the rat. J Neurosci 10:2638–2648 Bosman LW, Houweling AR, Owens CB, Tanke N, Shevchouk OT et al (2011) Anatomical pathways involved in generating and sensing rhythmic whisker movements. Front Integr Neurosci 5:53

Halata Z, Grim M, Bauman KI (2003) Friedrich Sigmund Merkel and his “Merkel cell”, morphology, development, and physiology: review and new results. Anat Rec A Discov Mol Cell Evol Biol 271:225–239Diamond ME, von Heimendahl M, Knutsen PM, Kleinfeld D, Ahissar E (2008) ‘Where’ and ‘what’ in the whisker sensorimotor system. Nat Rev Neurosci 9:601–612 Smith EM, Pang H, Cirrincione C, Fleishman S, Paskett ED et al (2013) Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial. JAMA 309:1359–1367 Cahusac PM, Senok SS (2006) Metabotropic glutamate receptor antagonists selectively enhance responses of slowly adapting type I mechanoreceptors. Synapse 59:235–242 Hires SA, Efros AL, Svoboda K (2013) Whisker dynamics underlying tactile exploration. J Neurosci 33:9576–9591 Blake DT, Johnson KO, Hsiao SS (1997) Monkey cutaneous SAI and RA responses to raised and depressed scanned patterns: effects of width, height, orientation, and a raised surround. J Neurophysiol 78:2503–2517

Yan Z, Zhang W, He Y, Gorczyca D, Xiang Y et al (2013) Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation. Nature 493:221–225 Rao RD, Michalak JC, Sloan JA, Loprinzi CL, Soori GS et al (2007) Efficacy of gabapentin in the management of chemotherapy-induced peripheral neuropathy: a phase 3 randomized, double-blind, placebo-controlled, crossover trial (N00C3). Cancer 110:2110–2118 Senok SS, Baumann KI, Halata Z (1996) Selective phototoxic destruction of quinacrine-loaded Merkel cells is neither selective nor complete. Exp Brain Res 110:325–334 FOSTER PARENT-KID RELATIONSHIP: This sensory discs set strengthens the interaction between parents and children, increase the time spent together, and make the parent-child relationship more intimate. Hama A, Takamatsu H (2016) Chemotherapy-induced peripheral neuropathic pain and rodent models. CNS Neurol Disord Drug Targets 15:7–19

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We’ve been playing with it for a few days now. Everyone loves the varied sensory experience as you walk from piece to piece. It’s sort of like an ever changing foot massage. Tachibana T, Endoh M, Fujiwara N, Nawa T (2005) Receptors and transporter for serotonin in Merkel cell-nerve endings in the rat sinus hair follicle. An immunohistochemical study. Arch Histol Cytol 68:19–28 Johansson RS, Flanagan JR (2009) Coding and use of tactile signals from the fingertips in object manipulation tasks. Nat Rev Neurosci 10:345–359

Smith KR Jr (1970) The ultrastructure of the human Haarscheibe and Merkel cell. J Invest Dermatol 54:150–159 Diamond J, Holmes M, Nurse CA (1986) Are Merkel cell-neurite reciprocal synapses involved in the initiation of tactile responses in salamander skin? J Physiol 376:101–120FUN MATCHING GAME: With little matching circular toys prepared for the large discs, they feature the similar textured surfaces, pairing them together by feet can be challenging and fun when blindfolded (Eye mask included).