MAX Absorption, Vitamin B12 Sublingual Liquid Drops, 3000mcg Methylcobalamin Per Serving, 60 Servings, Non-GMO, Vegan Friendly

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Ultimately, consulting a doctor is the safest way to determine which vitamin B12 supplement is best for you. SUMMARY The FNB did not establish a UL for vitamin B12 because of its low potential for toxicity [ 1]. Even at large doses, vitamin B12 is generally considered to be safe because the body does not store excess amounts. Interactions with Medications

Doets EL, In 't Veld PH, Szczecińska A, Dhonukshe-Rutten RA, Cavelaars AE, van 't Veer P, et al. Systematic review on daily vitamin B12 losses and bioavailability for deriving recommendations on vitamin B12 intake with the factorial approach. Ann Nutr Metab 2013;62:311-22. [ PubMed abstract] Vogiatzoglou A, Smith AD, Nurk E, Berstad P, Drevon CA, Ueland PM, et al. Dietary sources of vitamin B-12 and their association with plasma vitamin B-12 concentrations in the general population: the Hordaland Homocysteine Study. Am J Clin Nutr 2009;89:1078-87. [ PubMed abstract] Liquid vitamin B12 is not the only form of vitamin B12 supplements. Pill capsules and gummies are commonly available oral options.

Complications of vitamin B12 or folate deficiency anaemia

Most manufacturers also recommend a specific dosage. Still, it’s best to consult with your doctor first, since nutrient needs vary from person to person and liquid vitamin B12 supplements could interact with other medications or supplements.

While these lozenges are sugar free, they do contain mannitol, a sugar alcohol, and sucralose, an artificial sweetener. Some people find these additives lead to digestive upset, but at low doses (as they are in these lozenges), they are less likely to be cause for concern. You should be aware that this supplement contains soy, so it is not suitable if you have a soy allergy. People taking certain long-term medications, such as metformin and proton pump inhibitors, may also benefit from a supplement, as these medications can affect absorption of vitamin B12. The most common form of B12 in supplements is cyanocobalamin. Titcomb says, “Cyanocobalamin is a great option as it's a more stable compound and typically cheaper as well.”Bhargava R, et al. (2016). A randomized controlled trial of omega 3 fatty acids in rosacea patients with dry eye symptoms. In addition to oral dietary supplements, vitamin B12 is available in sublingual preparations as tablets or lozenges [ 22]. Evidence suggests no difference in efficacy between oral and sublingual forms [ 25, 26]. Prescription medications For reference, these are the Recommended Dietary Allowances (RDA) for vitamin B12 by sex and age group — indicating the daily amount needed for healthy individuals ( 25): Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Vitamin B12 is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement and a prescription medication. Because vitamin B12 contains the mineral cobalt, compounds with vitamin B12 activity are collectively called cobalamins [ 1]. Methylcobalamin and 5-deoxyadenosylcobalamin are the metabolically active forms of vitamin B12. However, two others forms, hydroxycobalamin and cyanocobalamin, become biologically active after they are converted to methylcobalamin or 5-deoxyadenosylcobalamin [ 1-3].