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Broccoli Sprout Extract by LLS | Contains Activated Sulforaphane | 60 Capsules | 18,000mg of Whole Plant Equivalent per Serving | Sulforaphane Supplement | Potent Antioxidant Content

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Jiang X, Liu Y, Ma L, et al. Chemopreventive activity of sulforaphane. Drug Des Devel Ther. 2018;12:2905-2913. doi:10.2147/DDDT.S100534 Yuan GF, Sun B, Yuan J, Wang QM. Effects of different cooking methods on health-promoting compounds of broccoli. J Zhejiang Univ Sci B. 2009;10(8):580-588. doi:10.1631/jzus.B0920051 Causes: Coronary heart disease. [Online]. NHS. Last Updated: .. Available at: https://www.nhs.uk/conditions/coronary-heart-disease/causes/ [Accessed 6 December 2022].

While inflammation doesn’t sound like a big deal, it’s an underlying cause of many other serious conditions. A little inflammation when you stub your toe is a perfectly normal reaction and helps heal any damage. There is a small amount of natural caffeine from the Phytofare Green Tea complex, which is 6% caffeine, roughly 10mg.

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The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Publisher’s Note

One study showed that a daily dose of sulforaphane dramatically reduced the size and number of cancer stem cells (x). Another study showed that consuming sulforaphane can help regulate key enzymes and immune system reactions that protect the body from cancer (x). This means broccoli extract may not only be useful for those who already have cancer, but could also prevent it altogether. Improves Digestion Animal, test-tube, and human studies have indicated that sulforaphane may offer a number of health benefits. May Have Anticancer EffectsKeep in mind that these studies use a concentrated form of sulforaphane, so it’s unclear whether the amounts found in fresh foods have the same effect. Lozanovski VJ, Polychronidis G, Gross W, et al. Broccoli sprout supplementation in patients with advanced pancreatic cancer is difficult despite positive effects-results from the POUDER pilot study. Invest New Drugs. 2020;38(3):776-784. doi:10.1007/s10637-019-00826-z Along with vitamin K, the choline in broccoli can help maintain and improve cognition. This has been measured in cognitive-performance tests and in healthy white-matter volumes of the brain (x). Tříska J, Balík J, Houška M, Novotná P, Magner M, Vrchotová N, Híc P, Jílek L, Thorová K, Šnurkovič P, Soural I. Factors Influencing Sulforaphane Content in Broccoli Sprouts and Subsequent Sulforaphane Extraction. Foods. 2021 Aug 19;10(8):1927. doi: 10.3390/foods10081927. PMID: 34441704; PMCID: PMC8394606.

Glucoraphanin — the precursor to sulforaphane — supplements are also available combined with myrosinase for activation. These are marketed as a way of increasing sulforaphane production in your body. org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Type 2 diabetes: Overview. [Updated 2020 Oct 22].Available from: https://www.ncbi.nlm.nih.gov/books/NBK279509/ For instance, sulforaphane may benefit heart health by reducing inflammation. Inflammation may lead to narrowing of your arteries — a major cause of heart disease ( 14, 15). Try steaming broccoli for a few minutes to soften it and bring out a sweeter flavor. You can also mix it with other vegetables for a nutrient boost. Work in an industry that involves frequent use of cleaning products, fumes, or work in a factory environmentYagishita Y, Fahey JW, Dinkova-Kostova AT, Kensler TW. Broccoli or sulforaphane: Is it the source or dose that matters? Molecules. 2019;24(19):3593. doi:10.3390/molecules24193593 Typically, cruciferous vegetables are not consumed immediately after harvesting. Therefore, the storage and processing of such vegetables have a significant impact on glucosinolate content and the health benefit of consumption ( Björkman et al., 2011; Barba et al., 2016). This is variable depending on the cultivar, plant tissue, and growth stage of the plant ( Galgano et al., 2007). Freezing has been shown to result in higher retention of glucosinolates compared to refrigeration. Storage of broccoli at 6°C for 35days resulted in a sulforaphane loss of 29%, compared to losses of approximately 13% after freezing at −18°C for 60days. Moreover, the reduction in glucosinolates measured after freezing was associated with steam-blanching prior to freezing ( Galgano et al., 2007). Storage in darkness has been shown to decrease the content of aliphatic glucosinolates ( Casajús et al., 2020). Current epidemiological evidence suggests that cruciferous vegetables play a key role in muscle and bone health, possibly due to the presence of glucosinolates and isothiocyanates. For example, in a large cohort of older community-dwelling women ( n= 1,468, ≥70years), women with the highest cruciferous (>44g/day) and allium (>11g/day) vegetable intake had 28 and 34% lower relative hazards for a fracture-related hospitalization over 14.5years, respectively ( Blekkenhorst et al., 2017b). Similarly, greater cruciferous and allium vegetable intake was associated with 22 and 26% lower relative hazard ratio for an injurious fall-related hospitalization over this time, respectively ( Sim et al., 2018). Although not specifically examining the role of glucosinolates, these studies demonstrate the potential importance of a diet rich in glucosinolates for musculoskeletal health. Muscle That said, population studies have linked a higher dietary intake of cruciferous vegetables like broccoli with a significantly reduced risk of cancer ( 11). Previous cell-based and human studies have indicated that sulforaphane exposure is associated with decreased breast cancer progression, including initiating cell cycle arrest and apoptosis ( Kuran et al., 2020). Sulforaphane treatment led to the inhibition of cell proliferation of breast cancer cells lines, MCF-7 and MDA-MB-231 and provoked cytotoxic activity by changing cysteine residues of the promyelocytic leukemia protein, known to promote proliferation of the MCF-7 breast cancer cell line ( Alhazmi et al., 2020). Sulforaphane has also been shown to modify cell migration and expression of epithelial mesenchymal transition markers that play a large role in breast cancer metastasis ( Bagheri et al., 2020).

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