Improved Medihoney Gel Wound and & Burn Dressing from Derma Sciences, 0.5 oz,

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Jull et al. 15 found that, in one trial, there was no significant difference in healing between honey and saline gauze at 16 weeks or in negative wound swabs at four weeks. 15 In another trial, the mean time to surgical closure was not significantly different between honey and povidone-iodine dressing but it was unclear whether the wounds actually healed. 15 Adverse events were not described well enough to be reported in the SR. 15 The authors of the HTA identified an additional RCT of Manuka-honey dressing versus conventional dressing and found there was no statistically significant difference in the mean duration of healing. 12 There was not enough evidence to comment on honey’s effect on infection in diabetic foot ulcer. 12 While care has been taken to ensure that the information prepared by CADTH in this document is accurate, complete, and up-to-date as at the applicable date the material was first published by CADTH, CADTH does not make any guarantees to that effect. CADTH does not guarantee and is not responsible for the quality, currency, propriety, accuracy, or reasonableness of any statements, information, or conclusions contained in any third-party materials used in preparing this document. The views and opinions of third parties published in this document do not necessarily state or reflect those of CADTH. Three SRs 13 , 15 , 16 performed MAs, and the HTA 12 and two SRs 14 , 17 did not perform any quantitative analysis.

YaghoobiR, et al. (2013). Evidence for clinical use of honey in wound healing as ananti-bacterial, anti-inflammatory anti-oxidant and anti-viral agent: A review. Second, Manuka honey contains a much higher concentration of methylglyoxal (MGO) than regular honey. MGO is an organic compound known for its antibacterial and antiviral properties.Medical researchers have long proven that the pH of a wound (specifically the surface area) influences all of the processes that occur at the cellular level over the course of healing. Honey is unique among sugars because of its acidity and low pH (3.2 to 4.5). This pH level is low enough to inhibit the growth of a number of dangerous bacterial pathogens: E. coli, Salmonella and P. aeruginosa are just a few examples among others. The low pH level of honey and subsequent capability to regulate the acidity of the wound environment and surrounding tissue is a crucial component in honey's ability to heal. If you have any questions about applying honey to your wound, follow up with a physician. Types of honey used on wounds MEDIHONEY looks similar in appearance and texture to traditional store-bought honey, but it’s not a sweetener. Instead, it provides an all-natural way to treat open wounds, preventing gangrene and infection. Often, wounds that have progressed carry a malodorous smell. MEDIHONEY has also been shown to decrease odors that may accompany wounds. People who live with poorly healing wounds tend to spend most of their time at home, due to pain and mobility issues. As such, these folks tend to be at risk for social isolation. Unpleasant wound odor can add insult to injury by embarrassing the patient and discouraging visitors. For the most part, wound odor is the result of both aerobic and anaerobic bacteria living within the necrotic (or rotten) wound tissue. The debridement properties of MEDIHONEY work to reduce the necrotic tissue The remarkable debriding action of honey that has been noted by many would also assist in this by removing slough which is a rich source of bacteria to stimulate an inflammatory response ( 19).

Medihoney is a mixture of two honeys derived from Australia and New Zealand containing glucose oxidase and Leptospermum compounds which contribute to its antibacterial activity.MEDIHONEY is a brand name wound and burn gel made from 100% Leptospermum (Manuka) honey. Manuka honey is unique in that it has antibacterial and bacterial resistant properties, meaning it prevents bacteria from building a tolerance to its beneficial effects. We’ve created an FAQ for those new to wound care and MEDIHONEY. This article answers the following: Kateel et al. 14 described their literature search as “exhaustive” but listed a limited number of key words that were searched in the literature. The authors also did not specify how study selection and data extraction were performed. 14 There was no list of excluded studies provided in three SRs. 13 , 14 , 16 The HTA 12 and four of the five SRs 13 , 15 – 17 reported comprehensive literature search strategies and study selection and data extraction was performed in 12 , 13 , 15 , 16 , 17 Kateelet al, 14 did not specify how their literature search or selection and extraction were performed. The included SRs reported primary study and patient characteristics, with the exception of Vandamme et al. 17 who did not report patient characteristics. 17

Apply the MEDIHONEY gel or paste directly to the wound. If you’re using a calcium alginate dressing, use sterile scissors to resize it, and then gently apply the dressing to the wound bed. Honey is a sugary, syrupy substance that has been shown to have bioactive components that can help heal wounds.

When using MEDIHONEY will I need any extra supplies?

MediHoney® dressings are made with a special honey that is derived from the nectar of the Leptospermum plant. This type of honey has unique properties that have been scientifically verified and shown in clinical trials and by other clinical evidence to be effective for the management of wounds and burns. 1-3 During initial use of the dressing (depending on wound exudate levels, interstitial fluid, and edema surrounding the wound), the dressings’ high osmotic potential may contribute to increased exudate, which could lead to maceration if the excess moisture is not managed appropriately. Manage additional moisture by adding an absorptive cover dressing and/or adjusting the frequency of dressing change.

Medical-grade honey, most recognized under the brand-name MEDIHONEY by Derma Sciences, is derived from the flower of the Manuka plant ( Leptospermum) of New Zealand, the most studied of all honey types. The source of the nectar finely tunes the properties of the honey, determining flavor, color and, in this case, medicinal benefits. Manuka honey offers an antibacterial environment that is superior to ordinary honey. In some countries, sterilized MEDIHONEY is available as a prescription. MEDIHONEY is a registered medical device in the United Kingdom and Australia; in the US, medical-grade honey dressings are being used in healthcare settings more frequently than ever before. While this is more of an idea than something that is proven, it’s important to be aware of the risks, according to the journal Wilderness & Environmental Medicine. Ineffective In our paediatric oncology department at the Children's Hospital Medical Centre, University of Bonn, Germany most patients suffer from a profoundly suppressed immune system, due to their underlying disease (i.e. leukemia) ( 1) and the chemotherapy they undergo. This frequently results in wound healing problems ( 2, 3), leaving the patient susceptible to wound infections. Unfortunately these infections spread easily in immunocompromized patients and can cause secondary potentially life-threatening bloodstream infections ( 4).Kamaratos AV, Tzirogiannis KN, Iraklianou SA, Panoutsopoulos GI, Kanellos IE, Melidonis AI. Manuka honey-impregnated dressings in the treatment of neuropathic diabetic foot ulcers. Int Wound J. 2012 ; 9: 1-7. If you care for a loved one with underlying health problems like diabetes or venous insufficiency, MEDIHONEY can reduce the risk of infections, support the removal of necrotic tissue, and encourage the body’s natural wound healing process. Keep in mind that it’s best that MEDIHONEY be on the skin for 12-24 hours at a time for maximum effectiveness. If you or your loved one is having a hard time keeping the dressing intact, soak a gauze dressing in the MEDIHONEY (or use the MEDIHONEY square dressing) and apply it directly on the wound, then top with an abdominal pad dressing. When using MEDIHONEY will I need any extra supplies? Until recent years, the use of honey as an occlusive dressing for wounds and burns was considered a natural, but unproven, alternative to traditional wound management products. Today, researchers have caught up with ancient wisdom and the use of medical-grade honey for the treatment of wounds is supported by a growing body of scientific evidence. Yes. Due to the osmotic potential there can be an increase in exudate and wound fluid to the wound area. Applying a skin protectant to the surrounding skin will help to prepare and protect the area from excess moisture and fluid.