2 Pack 210g Activated Charcoal Whitening Toothpaste with Bamboo Charcoal Bamboo Tooth Whitener No Fluoride

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Bondemark L, Ruf S. Randomized controlled trial: the gold standard or an unobtainable fallacy? Eur J Orthod. 2015;37(5):457–61. Bagatin CR, Ito IY, Andrucioli MC, Nelson-Filho P, Ferreira JT. Corrosion in Haas expanders with and without use of an antimicrobial agent: an in situ study. J Appl Oral Sci Revista FOB. 2011;19(6):662–7. Mahdavi-Roshan M, Salari A, Emaminejad S, Parvinroo S, Ashouri A, Alizadeh I. The effect of oxymel syrup on some cardiovascular risk factors in overweight and obese people: a randomized controlled trial study. Tradit Integr Med. 2021. https://doi.org/10.18502/tim.v6i3.7307. The primary pathogenic mechanism of dental caries initiation is lactic acid production by dental biofilm bacteria [ 28]. Acidogenic Lactobacilli spp. and Streptococcus mutans are the principal pathogens of dental plaque biofilm [ 29]. Although plaque removal during toothbrushing is mainly accomplished through mechanical action of toothbrushes, the use of appropriate toothpaste can enhance the antibacterial efficacy [ 30]. The aim of the present randomized controlled clinical trial was to compare the antibacterial efficacy of herbal toothpaste containing Bamboo salt with a non-herbal toothpaste as control, and it was observed that both toothpaste types reduced the Streptococcus mutans and Lactobacillus counts of saliva equally. Prasanth M. Antimicrobial efficacy of different toothpastes and mouthrinses: an in vitro study. Dent Res J. 2011;8(2):85.

Bamboo Salt is a common ingredient in a lot of Korean Toothpastes. This stems from the age-old practice of Koreans brushing their teeth with salt to keep them clean, act as a natural bleach as well as a natural disinfectant. Nakano K, Nomura R, Matsumoto M, Ooshima T. Roles of oral bacteria in cardiovascular diseases-from molecular mechanisms to clinical cases: cell-surface structures of novel serotype k Streptococcus mutans strains and their correlation to virulence. J Pharmacol Sci. 2010;113(2):120–5.To the best of our knowledge, no clinical studies have ever investigated the antimicrobial efficacy of Bamboo salt on cariogenic oral bacteria before. Nowadays, dentistry has evolved from a practice-based medical discipline to an evidence-based one. A substantial number of herbal extracts have been incorporated into oral hygiene products such as toothpaste or mouthwash, due to their proposed antimicrobial effects. Although the antimicrobial efficacy of some of them have already been demonstrated in clinical studies, evidence regarding this issue remains limited [ 35– 37]. As a health professional, it is important to be open minded and constantly learn about new technology that is constantly evolving. Nano hydroxyapatite has been used for many years in other parts of the world, and shown so many benefits from biocompatibility, relief in sensitivity, and its benefits in remineralization; restoring mineral dentistry and smoothness. I believe offering options to patients is essential when research shows its benefits. Co-application of brushing with toothpaste containing certain chemical agents helps remove pathogenic biofilm and reduces bacterial repopulation on the enamel. Toothbrushing is associated with a decrease in oral bacterial levels and maintenance of a healthy balance of oral flora on tooth surfaces [ 10]. Typically, conventional toothpaste types contain triclosan and fluoride as main antibacterial ingredients. It has been proven that these ingredients have anti-cariogenic properties [ 11]. In recent years, there has been an increased interest in therapeutic herbal ingredients worldwide, due to reduced side effects and better availability, leading to the popularity of herbal toothpastes. With the increasing availability of herbal toothpaste brands on the market, the efficacy of these products on oral bacteria has been studied extensively in recent years [ 12, 13, 14, 15, 16, 17, 18].

Pradeep A, Agarwal E, Naik SB. Clinical and microbiologic effects of commercially available dentifrice containing aloe vera: a randomized controlled clinical trial. J Periodont. 2012;83(6):797–804.Moon J-H, Shin H-A, Rha Y-A, Om A-S. The intrinsic antimicrobial activity of bamboo salt against Salmonella enteritidis. Mol Cell Toxicol. 2009;5(4):324–7. According to previous in-vitro studies, Bamboo salt is proposed to exert a variety of therapeutic effects, making it a potentially suitable ingredient for natural toothpastes [ 31]. One of them is the ability of Bamboo salt to remineralize incipient enamel lesions [ 23, 32]. In an in vitro study by Choi et al., a significant improvement in surface hardness of artificial caries-like enamel lesions was observed using the Bamboo salt-sodium fluoride toothpaste [ 23]. A synergic remineralization potential of Bamboo salt and sodium fluoride was later confirmed in an in vitro study by Kim et al., demonstrating a higher increase in surface hardness by combining both agents, compared to using them separately [ 32]. Choi C-H. Effects of bamboo salt on dental caries prevention. J Korea Dent Assoc. 2012;50(9):552–7. Furthermore, due to the competitive nature of the industry, many leading brands of Korean toothpaste feature innovative formulas for improved dental protection. Often times this will include the use of clinically proven ingredients like xylitol to reduce cavity-causing bacteria and promote healthy teeth. The bottom line is that when shopping for a quality Korean toothpaste it’s important to make sure that it offers plenty of fluoride. When it comes to toothpaste, finding something with fluoride is essential for preventing cavities and other oral health issues. Fluoride works by making teeth stronger and harder, and it helps to reduce the amount of acid that can lead to tooth decay. Without it, toothpaste would simply act as something that helps to remove the build-up of plaque and maybe freshen the breath.

Due to the comparable efficacy of the investigated herbal toothpaste with conventional toothpaste, it potentially qualifies as a complementary agent for self-care oral hygiene procedures. I've been a dentist for 16 years and this is the only brand of fluoride-free toothpaste alternative that I recommend to my patients. I've been using this toothpaste myself as someone who has fluorosis since it first came out and I've been so impressed with everything about it. Having personally experienced the appearance of the long lasting effects of demineralized, brown, chalky looking spots on my teeth from braces and having fluorosis, I can say that this toothpaste definitely delivers improved visible results. Hashemi MS, Hashempur MH, Lotfi MH, Hemat H, Mousavi Z, Emtiazy M, et al. The efficacy of asafoetida (Ferula assa-foetida oleo-gum resin) versus chlorhexidine gluconate mouthwash on dental plaque and gingivitis: a randomized double-blind controlled trial. Eur J Integr Med. 2019;29:100929. Another therapeutic property of Bamboo salt as toothpaste ingredient is its inhibitory effect on cytokines involved in gingival inflammation. In a molecular study on gingival fibroblasts, a reduction in IL-1β, IL-8, TNF-α was observed following the application of Bamboo salt and sodium fluoride, thereby enhancing gingival resistance to inflammation [ 33]. The anti-gingivitis effect of Bamboo salt was further confirmed in a randomized controlled clinical trial comparing a Bamboo salt toothpaste with another herbal toothpaste containing Centella Asiatica [ 34].

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Park BJTH, Kamei K, Matsuzawa T, Hyon S-H, Park J-C. In vitro antifungal activity of epigallocatechin 3-O-Gallate against clinical isolates of dermatophytes. Yonsei Med J. 2011;52(3):535. Wang W, Tao R, Tong Z, Ding Y, Kuang R, Zhai S, et al. Effect of a novel antimicrobial peptide chrysophsin-1 on oral pathogens and Streptococcus mutans biofilms. Peptides. 2012;33(2):212–9. Liu Y, Meng Y, Wu M, Zhang Q. A two-year longitudinal study of the effectiveness of the CRT® bacteria test in evaluating caries risk in three-year-old children. Evid Based Complement Altern Med. 2021. https://doi.org/10.1155/2021/7488855.

The inclusion of herbal antibacterial agents in the composition of toothpastes is becoming increasingly popular, due to lower side effects. The present study intended to investigate the antibacterial efficacy of a herbal toothpaste containing Bamboo salt on cariogenic oral bacteria. Methods Lee H-J, Park A-R, Oh H-N. Effects of Bamboo salt with sodium fluoride on the prevention of dental caries. J Dent Hyg Sci. 2019;19(4):288–93. Kumar PS, Anand Meganathan SS, Sampath V, Sekar M. Effect of proanthocyanidin and bamboo salt on the push-out bond strength of an epoxy resin sealer to sodium hypochlorite-treated root dentin: an in vitro study. J Conserv Dent: JCD. 2019;22(2):144. Co-application of brushing with toothpaste containing certain chemical agents helps remove pathogenic biofilm and reduces bacterial repopulation on the enamel. Toothbrushing is associated with a decrease in oral bacterial levels and maintenance of a healthy balance of oral flora on tooth surfaces [ 10]. Typically, conventional toothpaste types contain triclosan and fluoride as main antibacterial ingredients. It has been proven that these ingredients have anti-cariogenic properties [ 11]. In recent years, there has been an increased interest in therapeutic herbal ingredients worldwide, due to reduced side effects and better availability, leading to the popularity of herbal toothpastes. With the increasing availability of herbal toothpaste brands on the market, the efficacy of these products on oral bacteria has been studied extensively in recent years [ 12– 18]. Regarding the antimicrobial efficacy of Bamboo salt toothpaste, a recent in-vitro study by Lee et al. (2019) investigated the efficacy of Bamboo salt combined with sodium fluoride on streptococcus mutans. Various properties attributed to the cariogenesis of this microorganism including its growth, acid production, adherence to glass beads, and expression of gtfB, gtfC, gtfD, and ftf genes were significantly restrained by the Bamboo salt and sodium fluoride mixture. It was concluded that Bamboo salt and sodium fluoride can synergically act in inhibiting the cariogenic potential of Streptococcus mutans [ 21], which is consistent with the results of the present in-vivo study.Sivakumar P, Geetha R. In vitro study of anti-bacterial efficacy of herbal toothpastes vs triclosan and fluoride containing control. J Pharm Sci Res. 2016;8(7):680. Greenwall L, Wilson N. Charcoal toothpastes: what we know so far. Clinical Pharmacist. 2017;9(8). doi:10.1211/PJ.2017.20203167 Insan’s Bamboo Salt Toothpaste is one of the Best Korean toothpastes in the market. It contains natural ingredients, disinfectants help reduce bacteria, green tea extracts prevent gum inflammation and it helps keep your teeth healthy. Steinberg D, Mor C, Dogan H, Kaufmann D, Rotstein I. Formation of Streptococcus mutans biofilm following toothbrushing with regular and whitening toothpastes. Am J Dent. 2003;16(1):58–60.