Broccoli Sprout Extract by LLS | Contains Activated Sulforaphane | 60 Capsules | 18,000mg of Whole Plant Equivalent per Serving | Sulforaphane Supplement | Potent Antioxidant Content

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Lack of effect of oral sulforaphane administration on Nrf2 expression in COPD: A randomized, double-blind, placebo controlled trial. Of course, if someone has a sensitivity or allergy to cruciferous vegetables, that person should avoid consuming them. That said, dose ranges for intraperitoneal administration appears to provide roughly equivalent pharmacological efficacy to oral dosing with sulforaphane, presumably reflecting the excellent bioavailability of this agent.Various groups have since synthesized it, but Talalay and Zhang were the first to isolate it from broccoli [ 13] and to demonstrate its cancer protective properties [ 14]. Studies show that sulforaphane from broccoli sprout extract is particularly important in detoxifying and reducing the impact of environmental toxins such as those from pollution and heavy metals. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Dietary approach to attenuate oxidative stress, hypertension, and inflammation in the cardiovascular system. Sulforaphane induces thioredoxin through the antioxidant-responsive element and attenuates retinal light damage in mice.

In these foods, it’s in the inactive form glucoraphanin that belongs to the glucosinolate family of plant compounds. It is carried out by the bacterial microflora of the gastrointestinal tract and can be greatly reduced by antibiotic treatment or mechanical bowel cleansing [ 26].There isn't enough reliable information to know if broccoli sprout extract is safe to use when pregnant or breast-feeding. Since first isolated from broccoli and demonstrated to have cancer chemoprotective properties in rats in the early 1990s, over 3000 publications have described its efficacy in rodent disease models, underlying mechanisms of action or, to date, over 50 clinical trials examining pharmacokinetics, pharmacodynamics and disease mitigation. Taken together, these correlations suggest that the glucosinolates function for protection of the plant against a wide array of environmental challenges. Consuming broccoli sprouts and other cruciferous foods with high levels of sulforaphane have been linked to reduced risks of ovarian, prostate and colorectal cancers by promoting apoptosis (when cells that are old and unwanted essentially ‘die’) and reducing metabolites that potentially promote breast cancer.