Page 214: “If you have autoimmune disease, significant gut issues, or evidence of inflammation, I would recommend starting with at least a Tier 2 carnivore diet or, preferably, Tier 3. The issue is that White Oak Pastures doesn’t just produce beef, and cows aren’t the only way carbon gets into the soil.

In patients with SIBO, the migrating motor complex appears to be hypoactive, allowing the populations of bacteria in the colon to move up into the small intestine, leading to an imbalance and a loss of diversity there. Only three of these studies measured LDL cholesterol, so The Carnivore Code’s conclusions about LDL are somewhat misleading.Although it wasn’t a randomized controlled trial, the Virta Health study was a high-quality non-randomized controlled trial that reported that a very-low-carbohydrate (ketogenic) diet plus intensive support is helpful for managing type 2 diabetes. A third meta-analysis in children didn’t find evidence that fiber improves treatment success for constipation.

There are a TON of pictures throughout the first 83 pages, so I assumed there'd be a picture for every recipe. The book cites a study that establishes that Neanderthals and Denisovans didn’t have duplications of the salivary amylase gene, supporting the idea that this duplication occurred after Homo sapiens split from those lineages.The largest and most recent meta-analysis of fiber and constipation we found reports that fiber supplementation does improve treatment outcomes in adults with constipation, and larger amounts of fiber yield better results.

Insulin resistance is a risk factor for cardiovascular disease, and these studies provide one mechanism to explain that, but none of them report that LDL becomes irrelevant or even beneficial in a person who is insulin-sensitive. This implies that regenerative agriculture may only be offsetting greenhouse gas emissions temporarily, after which soil carbon levels reach equilibrium and meat production once again results in high net greenhouse gas emissions. The book cites seven references to support its argument that “during the states of insulin resistance and inflammation, both the LDL particle and the intimal space get coated in ‘molecular velcro’ and become more sticky” (p. Clinical case series like this are a valid form of evidence but they’re much less convincing than gold-standard study designs like randomized controlled trials.In The Carnivore Code , Paul Saladino, MD, argues that humans evolved as carnivores and eating plant foods undermines our health and saps our vigor. In this context, we think it’s relevant that the book’s author Paul Saladino has publicly shared that he has extremely high LDL cholesterol (533 mg/dL) and LDL particle number (3,283 nmol/L).