Geerling G, Tauber J, Baudouin C, Goto E, Matsumoto Y, O’Brien T, Rolando M, Tsubota K, Nichols KK (2011) The international workshop on meibomian gland dysfunction: report of the subcommittee on management and treatment of meibomian gland dysfunction. Invest Ophthalmol Vis Sci 52:2050–2064. https://doi.org/10.1167/iovs.10-6997g Naviblef ® Wipes provide relief by removing secretions and eyelid and eyelash debris caused by allergic and inflammatory conditions associated with: Naviblef ® Intensive Care may be used to remove severe secretions from the eyelids and eyelashes caused by the following conditions: 1

Nichols KK, Foulks GN, Bron AJ, Glasgow BJ, Dogru M, Tsubota K, Lemp MA, Sullivan DA (2011) The international workshop on meibomian gland dysfunction: executive summary. Invest Ophthalmol Vis Sci 52:1922–1929. https://doi.org/10.1167/iovs.10-6997a Safety is of paramount importance to the pharmaceutical industry. VISUfarma makes every effort to provide helpful, accurate information which is compliant with industry regulations. Naviblef ® Intensive Care may be used to remove severe secretions from the eyelids and eyelashes caused by the following conditions:

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Naviblef ® Daily Care is a foam formulation containing Tea Tree Oil for the effective removal of excessive oil, pollen, ocular secretions or other debris from the eyelids that may lead to eye irritation, including blepharitis caused by Demodex and bacterial infestations or dry eye symptoms. 2 Naviblef ® Daily Care is recommended to be used as daily maintenance care for patients that have followed blepharitis treatment with Naviblef ® Intensive Care.

Wolkoff P, Nøjgaard JK, Troiano P, Piccoli B (2005) Eye complaints in the office environment: precorneal tear film integrity influenced by eye blinking efficiency. Occup Environ Med 62:4–12. https://doi.org/10.1136/oem.2004.016030 Remove the mask from its box and place it on a clean plate suitable for microwave use. Stay near the microwave oven while the mask is being heated. Make sure that the microwave tray rotates correctly during heating. MeiboPatch ® is a reusable ocular eye compress which can be heated using a microwave and applied to the eyelids. 1 The gentle heat can be used to treat Meibomian Gland Dysfunction (MGD), blepharitis, chalazion, crusting, cysts, eyelid inflammation and dry eye syndrome. 1The Meibopatch is a microwaveable eye mask for the treatment for Meibomian Gland Dysfunction (MGD), blepharitis, chalazions, crusting, cysts and dry eye syndrome. The definition and classification of dry eye disease (2007) report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop. Ocul Surf 5:75–92. https://doi.org/10.1016/s1542-0124(12)70081-2 Tauber J, Owen J, Bloomenstein M, Hovanesian J, Bullimore MA (2020) Comparison of the iLUX and the LipiFlow for the treatment of meibomian gland dysfunction and symptoms: a randomized clinical trial. Clin Ophthalmol 14:405–418. https://doi.org/10.2147/opth.S234008 Stapleton F, Alves M, Bunya VY, Jalbert I, Lekhanont K, Malet F, Na KS, Schaumberg D, Uchino M, Vehof J, Viso E, Vitale S, Jones L (2017) TFOS DEWS II epidemiology report. Ocul Surf 15:334–365. https://doi.org/10.1016/j.jtos.2017.05.003

Pang SP, Chen YT, Tam KW, Lin IC, Loh EW (2019) Efficacy of vectored thermal pulsation and warm compress treatments in meibomian gland dysfunction: a meta-analysis of randomized controlled trials. Cornea 38:690–697. https://doi.org/10.1097/ico.0000000000001907 Use the mask twice a day at the start of treatment and when symptoms have been relieved, you may be able to use it just once a day. Your eyecare specialist may assess the severity of your symptoms and advise you whether to use your mask more often. Naviblef ® Intensive Care is a foam formulation containing Tea Tree Oil intended for hygiene and the mechanical removal of severe ocular secretions and debris from eyelashes and eyelids. Viso E, Rodríguez-Ares MT, Abelenda D, Oubiña B, Gude F (2012) Prevalence of asymptomatic and symptomatic meibomian gland dysfunction in the general population of Spain. Invest Ophthalmol Vis Sci 53:2601–2606. https://doi.org/10.1167/iovs.11-9228 Naviblef ® Intensive Care is a foam formulation containing Tea Tree Oil intended for hygiene and the mechanical removal of severe ocular secretions and debris from eyelashes and eyelids. 1

We searched for randomized clinical trials (RCTs) in Embase, MEDLINE, the Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, Web of Science, and ClinicalTrials.gov up to 4 January 2021. The subjective symptoms, objective tests of dry eye, meibomian gland function, and the incidence of adverse events were evaluated. Results To investigate the efficacy and safety of a vectored thermal pulsation system (Lipiflow®) in the treatment of dry eye disease resulting from meibomian gland dysfunction (MGD). Methods Bron AJ, de Paiva CS, Chauhan SK, Bonini S, Gabison EE, Jain S, Knop E, Markoulli M, Ogawa Y, Perez V, Uchino Y, Yokoi N, Zoukhri D, Sullivan DA (2017) TFOS DEWS II pathophysiology report. Ocul Surf 15:438–510. https://doi.org/10.1016/j.jtos.2017.05.011

Naviblef ® Daily Care is a foam formulation containing Tea Tree Oil for the effective removal of excessive oil, pollen, ocular secretions or other debris from the eyelids that may lead to eye irritation, including blepharitis caused by Demodex and bacterial infestations or dry eye symptoms. seconds’ heating in a microwave oven with a power of 800 Watts is generally sufficient for MeiboPatch® to reach the desired temperature. Amano S, Inoue K (2017) Clinic-based study on meibomian gland dysfunction in Japan. Invest Ophthalmol Vis Sci 58:1283–1287. https://doi.org/10.1167/iovs.16-21374 MeiboPatch ®includes a unique temperature test strip which shows when it is ready for use. 1 This ensures it gets to the right temperature to effectively treat MGD but not too hot that it would burn, ensuring patient safety.Jeyalatha MV, Qu Y, Liu Z, Ou S, He X, Bu J, Li S, Reinach PS, Liu Z, Li W (2017) Function of meibomian gland: contribution of proteins. Exp Eye Res 163:29–36. https://doi.org/10.1016/j.exer.2017.06.009 Nelson JD, Shimazaki J, Benitez-del-Castillo JM, Craig JP, McCulley JP, Den S, Foulks GN (2011) The international workshop on meibomian gland dysfunction: report of the definition and classification subcommittee. Invest Ophthalmol Vis Sci 52:1930–1937. https://doi.org/10.1167/iovs.10-6997b Kasetsuwan N, Suwajanakorn D, Tantipat C, Reinprayoon U (2020) The efficacy between conventional lid hygiene and additional thermal pulsatile system in meibomian gland dysfunction patients treated with long-term anti-glaucoma medications in a randomized controlled trial. Clin Ophthalmol 14:2891–2902. https://doi.org/10.2147/opth.S259692 Donthineni PR, Das AV, Basu S (2020) Dry eye disease in children and adolescents in India. Ocul Surf 18:777–782. https://doi.org/10.1016/j.jtos.2020.07.019