Lemsip Cough Max for Mucus Cough & Cold 16 Capsules

Product Information

Phenylephrine overdose is likely to result in: nervousness, headache, dizziness, insomnia, increased blood pressure, nausea, vomiting, mydriasis, acute angle closure glaucoma (most likely to occur in those with closed angle glaucoma), tachycardia, palpitations, allergic reactions (e.g. rash, urticaria, and allergic dermatitis), dysuria, and urinary retention (most likely to occur in those with bladder outlet obstruction, such as prostatic hypertrophy). Additional symptoms may include, hypertension, and possibly reflex bradycardia. In severe cases confusion, seizures and arrhythmias may occur. However the amount required to produce serious phenylephrine toxicity would be greater than that required to cause paracetamol-related liver toxicity. Cetylpyridinium Chloride 3.0 mg /20ml dose Indications: Short term symptomatic relief of the symptoms of colds and flu, including

Due to the presence of caffeine, the product should be taken with care in patients with a history of peptic ulcers. Liver damage is possible in adults who have taken 10 g or more of paracetamol. Ingestion of 5 g or more of paracetamol may lead to liver damage if the patient has risk factors (see below). Paracetamol: Liver damage is possible in adults who have taken 10 g or more of paracetamol. Ingestion of 5g or more paracetamol may lead to liver damage if the patient has risk factors (see below). Drinking alcohol with Lemsip max flu lemon is best avoided because the combination of alcohol and paracetamol could increase the risk of side effects on your liver.Phenylephrine hydrochloride 12.2 mg Indications: For relief of the symptoms of colds and influenza, including the Phenylephrine hydrochloride: High blood pressure with headache, vomiting, Rarely, palpitations. Also, rare reports of allergic reactions and occasionally urinary retention in males. Monoamine oxidase inhibitors (including moclobemide): hypertensive interactions occur between sympathomimetic amines such as phenylephrine and monoamine oxidase inhibitors (see section 4.3). LEMSIP MAX COLD & FLU CAPSULES: Each capsule contains Paracetamol 500 mg, Caffeine 25 mg Phenylephrine hydrochloride 6.1 mg

Paracetamol: Paracetamol is absorbed rapidly and completely mainly from the small intestine, producing peak plasma levels after 15-20 minutes following oral dosing. The systemic availability is subject to first-pass metabolism and varies with dose between 70% and 90%. The drug is rapidly and widely distributed throughout the body and is eliminated from plasma with a T ½ of approximately 2 hours. The major metabolites are glucuronide and sulphate conjugates (>80%) which are excreted in urine.

Summary of medicine characteristics - LEMSIP COUGH MAX FOR CHESTY COUGH & COLD RELIEF CAPSULES

Caffeine/metabolites are excreted in human milk, but at therapeutic doses of the product, no effects on the breastfed new-borns/infants are anticipated. Do not take more than the recommended dose. You should also avoid taking more than one paracetamol-containing medicine at the same time, as this can easily result in exceeding the maximum dose of paracetamol. The antidiabetic medicines exenatide, lixisenatide and liraglutide may slow down the absorption of paracetamol into the bloodstream, so it might take longer to work if you're using one of these medicines to treat your diabetes. Ask your pharmacist for more advice. If you're taking medicines for high blood pressure you shouldn't take Lemsip max flu lemon as well, because the pseudoephedrine may make your blood pressure medicine less effective. Don't take Lemsip max flu lemon if you have taken a type of medicine called a monoamine oxidase inhibitor (MAOI) in the last 14 days. MAOIs include the antidepressants phenelzine, tranylcypromine, isocarboxazid and moclobemide, and the anti-Parkinson's medicines selegiline and rasagiline. This is because the combination of pseudoephedrine with these medicines could cause a dangerous increase in blood pressure (hypertensive crisis).

Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour. Plasma paracetamol concentration should be measured at 4 hours or later after ingestion (earlier concentrations are unreliable). Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion. The effectiveness of the antidote declines sharply after this time. If required the patient should be given intravenous N-acetylcysteine, in line with the established dosage schedule. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. Management of patients who present with serious hepatic dysfunction beyond 24 hours from ingestion should be discussed with the NPIS or a liver unit. Get emergency help immediately if any of the following symptoms of overdose occur while taking acetaminophen: Symptoms of overdose Epidemiological studies in human pregnancy have shown no ill effects due to paracetamol used in the recommended dosage. Phenylephrine overdose is likely to result in: nervousness, headache, dizziness, insomnia, increased blood pressure, nausea, vomiting, mydriasis, acute angle closure glaucoma (most likely to occur in those with closed angle glaucoma), tachycardia, palpitations, allergic reactions (e.g. rash, urticaria, allergic dermatitis), dysuria, urinary retention (most likely to occur in those with bladder outlet obstruction, such as prostatic hypertrophy). a) Is on long-term treatment with carbamazepine, phenobarbitone, phenytoin, primidone, rifampicin, St John's Wort or other drugs that induce liver enzymes, orThe rate of absorption of paracetamol may be increased by metoclopramide or domperidone and absorption may be reduced by cholestyramine. If you take Lemsip cough max for mucus cough and cold in the hour before or the six hours after taking colestyramine, the paracetamol is likely to be less effective. This is because colestyramine reduces the absorption of paracetamol from the gut.