Adults and adolescents aged 12 years and over should take two tablets every eight hours as needed, up to a maximum of six tablets in 24 hours. Kawada A, Hiruma M, Noguchi H, Ishibashi A. Fixed drug eruption induced by acetaminophen in a 12-year-old girl. Int J Dermatol. 1996;35:148-9. Indications: For the relief of symptoms of colds and influenza, including the relief of aches and pains, sore throat, headache, nasal Zimmerman HJ, Maddrey WC. Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure. Hepatology. 1995;22:767-73. Halevi A, BenAmitai D, Garty BZ. Toxic epidermal necrolysis associated with acetaminophen ingestion. Ann Pharmacother. 2000;34:32-4.

If you take Lemsip max day & night cold & flu relief in the hour before or the six hours after taking colestyramine, the paracetamol is likely to be less effective. This is because colestyramine reduces the absorption of paracetamol from the gut.Using more than one medicine with the same (or similar) active ingredients at the same time could lead to you exceeding the maximum dose or having a higher risk of side effects. Filipe PL, Freitas JP, Decastro JC, Silva R. Drug eruption induced by acetaminophen in infectious mononucleosis. Int J Dermatol. 1995;34:220-1. Adults aged 16 years and over should take two capsules every four to six hours as necessary, up to a maximum of four doses in 24 hours. Do not take more than eight capsules in 24 hours.

Common (1% to 10%): Peripheral edema, hypertension, hypotension, tachycardia, chest pain [ Ref] Metabolic This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately. Use with caution in An overdose of paracetamol is dangerous and capable of causing serious damage to the liver and kidneys. Get immediate medical advice if you or someone you know takes too much paracetamol, even if you feel well, because of the risk of delayed, serious liver damage.It's not known if phenylephrine passes into breast milk, or its effect on a nursing infant. When taken by mouth, decongestants such as phenylephrine can also temporarily decrease the production of breast milk with just one or two doses. Lemsip max should not be used by woman who are breastfeeding. Ask your doctor or pharmacist for further advice. Lemsip max cold and flu capsules should be used with caution in: This medicine is not recommended for use during pregnancy. In particular, it should not be taken in the third trimester, as ibuprofen may delay labour, increase the length of labour and cause complications in the newborn baby. Phenylephrine has blood vessel constricting effects that could restrict blood supply to the placenta, or cause problems for women with a history of pre-eclampsia. Some evidence suggests that NSAIDs should also be avoided by women attempting to conceive, as they may temporarily reduce female fertility during treatment and may also increase the risk of miscarriage or malformations. Seek further medical advice from your doctor, pharmacist or midwife. If this medicine is used in combination with quinolone antibiotics, such as ciprofloxacin or norfloxacin there may be an increased risk of seizures (fits). This may occur in people with or without a previous history of epilepsy or convulsions. Other medicines containing the same active ingredients

If you forget to take this medicine Do not take a double dose to make up for a forgotten dose. If you forget a dose, take it as soon as you remember it an then take the next dose at least 4 hours later.Adults, the elderly and children 16 years and over: One sachet every 4–6 hours as required. Do not take more than 4 sachets in 24 hours. Healthcare (UK) Ltd, Hull, HU8 7DS. Information about this product, including adverse reactions, precautions, contra indications,

Guccione JL, Zemtsov A, Cobos E, Neldner KH. Acquired purpura fulminans induced by alcohol and acetaminophen - successful treatment with heparin and vitamin-k. Arch Dermatol. 1993;129:1267-9. Prostaglandins are produced by the body in response to injury and certain diseases. One of their actions is to sensitise nerve endings, so that when that area is stimulated it causes pain (presumably to prevent us from causing further harm to the area). As paracetamol reduces the production of these nerve sensitising prostaglandins it's thought it may increase our pain threshold, so that although the cause of the pain remains, we can feel it less. If phenylephrine is taken with any of the following medicines, the combination may cause an increase in blood pressure. If you are already taking any of these medicines you should avoid taking this one as well:http://www.medicines.org.uk/emc/medicine/25517 for Lemon and http://www. medicines.org.uk/emc/medicine/23371 for Wild Berry and Hot Orange. People who have experienced bleeding from the gut or a hole (perforation) in the gut, as a result of previous use of an NSAID medicine. antiplatelet medicines to reduce the risk of blood clots or 'thin the blood', eg dipydridamole, clopidogrel, low-dose aspirin There may be an increased risk of side effects on the kidneys if ibuprofen is taken in combination with any of the following medicines: Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: